Parotid Gland Oncocytoma and Its Clinicopathological Approach: A Case Report
Abstract
Introduction: Oncocytoma is a benign tumor of the salivary glands consisting of oncocyte cells, occurring in approximately 2% of all salivary gland neoplasms, most of which occur in the parotid gland. This tumour most commonly occurs in the sixth to eighth decades of life, with a mean age of 64 years and without gender predilection. The clinical presentation is often misdiagnosed as pleomorphic adenoma, cystic lesion, and inflammation.
Case Presentation: A 63-year-old male, complained of a lump under the right ear, for 7 years ago. It feels painless and slightly enlarged since a month before surgery. Based on clinical examination suspected as benign cystic lesion due to inflammation and ultrasound suggesting a benign tumour mass with multiple lymphadenopathies at the right and left submandibular and right parotid. Then, the resected tumour continued for histopathological examination. Microscopically, the tumor cells are confined to the tissue. It consists of a uniform large polygonal cell with granular eosinophilic cytoplasm without any mitosis and necrotic area.
Conclusions: Oncocytoma is a rare benign tumor of the salivary glands, especially affecting the parotid gland. Clinical and radiologically it is often misdiagnosed, so histopathological examination is needed for diagnostic confirmation for the best patient outcomes
Keywords
DOI: 10.33371/ijoc.v19i1.1233
Article Metrics
Abstract View: 137, 
PDF Download: 113
References
Katabi N, Assaad A. Oncocytoma. In: El-Nagger AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, editors. World Health Organization Classification of Head and Neck Tumours. 4th ed. Lyon, France: International Agency for Research on Cancer; 2017.p.189-90.
McHugh JB. Major and Minor Salivary Glands. In: Goldblum JR, Lamps LW, McKenney JK, Myers JL editors. Rosai and Ackerman’s Surgical Pathology. 11th ed. Philadelphia: Elsevier; 2018.p.243-44.
Eroschenko VP. DiFiore’s Atlas of Histology with functional correlations. 12th ed. Philadelphia: Lipincott Williams and Wilkins; 2013.p.303-04.
Corvino A, Caruso M, Varelli C, et al. Diagnostic imaging of parotid gland oncocytoma: a pictorial review with emphasis on ultrasound assessment. J Ultrasound. 2021;24(3):241-7.
Imran S, Allen A, Shokouh-Amiri M, et al. Parotid oncocytoma: CT and pathologic correlation of a rare benign parotid tumor. Radiol Case Rep. 2019;15(1):31-4.
Alsanie I, Rajab S, Cottom H, et al. Distribution and Frequency of Salivary Gland Tumours: An International Multicenter Study. Head Neck Pathol. 2022;16(4):1043-1054.
Singh J, Chandra A, Srilatha T, et al. Oncocytoma of the parotid gland: A rare benign tumour. J Oral Maxillofac Pathol. 2023;27(1):41-4.
Sharma V, Kumar S, Sethi A. Oncocytoma Parotid Gland. Ann Maxillofac Surg. 2018;8: 330-32.
Rivera RD, Nelson BL. Sine Qua Non: Oncocytoma. Head Neck Pathol. 2022;16(4):1167-71.
Kammal WSWA, Azman M, Salleh AA, et al. Parotid gland oncocytic carcinoma: A rare entity in Head and Neck region. Malays J Pathol. 2020;42(2):283-86.
Lindberg MR, MD, Lamps LW, MD. Diagnostic Pathology: Normal Histology. 2nd ed. Philadelphia: PA. Elsevier; 2018:184-87.
Tyagi I, Das A. Essentials of Gross Pathology. 1st ed. New Delhi: CBS Publishers and Distributors; 2017:66.
Korbi AE, Jellali S, Njima M, et al. Parotid Gland Oncocytoma: A rare case and literature review. Journal of Medical Cases. 2019;146-9.
Lv K, Cao X, Geng D, Zhang J. Imaging features of parotid gland oncocytoma: a case series study. Gland Surg. 2021;10(3):870-6.
Elias N, Katherine P, Maria GD, Nikki G. A rare case of oncocytoma of the parotid gland with aggressive features and malignant potential: a case report. Journal of Otolaryngology-ENT Research. 2018;114-16.
Refbacks
- There are currently no refbacks.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Email this article 
